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Oxecta

Generic name: oxycodoneox-i-KOE-done ]
Drug class: Opioids (narcotic analgesics)

Medically reviewed by Philip Thornton, DipPharm. Last updated on Aug 23, 2023.

What is Oxecta?

Oxecta is an opioid pain medication. An opioid is sometimes called a narcotic.

Oxecta is an immediate release tablet used to treat moderate to severe pain.

Oxecta may also be used for purposes not listed in this medication guide.

Warnings

You should not use Oxecta if you have severe asthma or breathing problems, or a blockage in your stomach or intestines.

Oxecta can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take this medicine in larger amounts, or for longer than prescribed.

Oxecta may be habit-forming, even at regular doses. Take this medicine exactly as prescribed by your doctor. Never share the medicine with another person. MISUSE OF NARCOTIC PAIN MEDICATION CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

Tell your doctor if you are pregnant. Oxycodone may cause life-threatening withdrawal symptoms in a newborn.

Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with oxycodone.

Oxecta can cause severe constipation. Laxatives and/or stool softeners should be used in conjuction with this medicine.

Before using Oxecta

You should not use Oxecta if you are allergic to oxycodone, or if you have:

You should not use oxycodone unless you are already using a similar opioid medicine and are tolerant to it. Ask your doctor if you are not sure you are opioid-tolerant.

Oxecta may be habit forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away Oxecta to any other person is against the law.

Some medicines can interact with oxycodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

To make sure Oxecta is safe for you, tell your doctor if you have:

Tell your doctor if you are pregnant. If you use Oxecta while you are pregnant, your baby could become dependent on oxycodone. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

Oxycodone can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using Oxecta.

Do not give this medicine to a child without medical advice.

How should I use Oxecta?

Take Oxecta exactly as prescribed. Follow all directions on your prescription label. Oxecta can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Take each tablet with enough water to ensure complete swallowing immediately after placing the tablet in the mouth. Oxecta tablets must be swallowed whole. Do not crush or dissolve.

Do not pre-soak, lick or otherwise wet the Oxecta tablet prior to placing in the mouth.

Oxycodone may be habit-forming, even at regular doses. Take this medicine exactly as prescribed by your doctor. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH.

Do not stop using oxycodone suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using this medicine.

Never crush or break an Oxecta tablet to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death with the misuse of oxycodone and similar prescription drugs.

Store Oxecta at room temperature, away from heat, moisture, and light.

Keep track of the amount of medicine used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Always check your bottle to make sure you have received the correct pills (same brand and type) of medicine prescribed by your doctor. Ask the pharmacist if you have any questions about the medicine you receive at the pharmacy.

Do not keep leftover Oxecta tablets. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush any unused tablets down the toilet. Disposal of medicines by flushing is recommended to reduce the danger of accidental overdose causing death. This advice applies to a very small number of medicines only. The FDA, working with the manufacturer, has determined this method to be the most appropriate route of disposal and presents the least risk to human safety.

What happens if I miss a dose?

Since Oxecta is used when needed, you may not be on a dosing schedule. If you are on a schedule and you miss a dose, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and take the next dose at the regularly scheduled time. Do not take 2 doses at once unless instructed by your healthcare provider. If you are not sure call your healthcare provider.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An oxycodone overdose can be fatal, especially in a child or other person using the medicine without a prescription.

What should I avoid?

Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with Oxecta. Check your food and medicine labels to be sure these products do not contain alcohol.

Oxecta may impair your thinking or reactions. Avoid driving or operating machinery until you know how you are affected. Dizziness or severe drowsiness can cause falls or other accidents.

Grapefruit and grapefruit juice may interact with Oxecta and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.

Oxecta side effects

Get emergency medical help if you have any signs of an allergic reaction to Oxecta: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

Oxycodone is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common Oxecta side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Oxecta?

Some medicines can cause unwanted or dangerous effects when used with oxycodone. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking Oxecta with a sleeping pill, muscle relaxer, other pain medicine, or medicine for anxiety, depression, or seizures.

Other drugs may interact with oxycodone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Popular FAQ

Any drug that is classified as an "opioid" can cause constipation. Examples of commonly prescribed opioids that may cause this side effect include morphine, tramadol, fentanyl, methadone, hydrocodone, codeine and oxycodone. Continue reading

Immediate-release oxycodone has a half-life of just under 4 hours which means the pain-relieving effects of one dose will be gone within 6 to 24 hours, but it can remain detectable in saliva, urine, and hair for much longer. In saliva, oxycodone is detectable within minutes of taking it and lasts for up to 48 hours (2 days). Oxycodone is detectable in urine within 1 to 3 hours and will stay detectable for 1 to 4 days. Like most other opioids, oxycodone is detectable in hair for up to 90 days. Continue reading

How long opioid withdrawal lasts depends on the opioid you have been taking and whether it is a short-acting or long acting opioid.

If you have been using a short-acting opioid, acute opioid withdrawal lasts 4 to 10 days, with withdrawal symptoms starting 8 to 24 hours after last use.

If you have been using a long-acting opioid, acute opioid withdrawal lasts 10 to 20 days, with withdrawal symptoms starting 12 to 48 hours after last use. Continue reading

Immediate-release oxycodone starts to work quickly, within 10 to 30 minutes, but it may take up to 1 hour for it to be fully absorbed, and the full effects reached. Food can delay how quickly oxycodone takes to work, but not how much is absorbed. Continue reading

Oxycodone (also known as Oxy IR) and Oxycontin both contain oxycodone, but the main difference is that Oxycontin is the brand name of a long-acting form of oxycodone. Oxycontin releases oxycodone slowly and continuously over 12 hours and only needs to be given twice a day. Oxycodone is shorter-acting, with an average half-life of 3.2 hours, which means that half the dose of oxycodone is eliminated in 3.2 hours, which is why it is usually given four to six times a day to provide all-day pain relief. Oxycodone is usually given for acute pain, such as that following surgery or trauma, whereas Oxycontin may be given for chronic or long-term pain, such as that caused by cancer. Oxycontin should only be considered in those with chronic severe pain that have already found a trial of oxycodone to be beneficial. Continue reading

Withdrawal from oxycodone is likely to happen to people who have taken oxycodone consistently or misused oxycodone. Common symptoms of withdrawal include:

  • Anxiety
  • Cravings for oxycodone – these are one of the main symptoms that drive relapse
  • Diarrhea
  • Fast heartbeat
  • High blood pressure
  • Muscle aches
  • Nausea or vomiting
  • Sleep disturbances/Insomnia
  • Stomach cramps
  • Sweating.
Continue reading

More FAQ

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Oxecta only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.